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High Prescription Drug Costs Spark Debate


Journal of the American Medical Association - August 27, 2016 对应策略建议药物生产价格竞争和有成本效益的替代品。 Strategies suggested to produce price competition and cost-effective alternatives.

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For many Americans, a trip to the pharmacy can result in sticker shock. People in the United States pay more for their prescription drugs than anywhere else in the world.
Dr. Aaron Kesselheim, Brigham and Women's Hospital:
There's a lot of frustration about high drug costs, and how they impact the delivery of patient care.
CD: Dr. Aaron Kesselheim and his colleagues at Brigham and Women's Hospital reviewed the medical and health policy literature on prescription drug prices in the U.S. The researchers say high drug costs stem from several factors:
AK: The provision of market exclusivity that allows drug companies to charge whatever the market will bear, and then, limitations on payers and their ability to negotiate drug prices, and the limitations on competition that might drive drug prices down.
CD: The study appears in JAMA - Journal of the American Medical Association.
AK: Another factor [is that] a lot of physicians don't know what the price of the drugs are to patients, and so, will prescribe drugs without thinking about the price of the product.
CD: This contributes to patients sometimes not filling prescriptions and spreading out doses or splitting pills to reduce costs.
AK: We need more education for physicians and patients about the implications of high drug prices on the delivery of care.
CD: Also, more information on identifying high- and low-value drugs, so resources aren't wasted.
AK: And ensuring that there is both reasonable periods of market exclusivity, as well as adequate competition, when those market exclusivity periods end.
CD: And timely availability of high-quality and safe generic drugs.
AK: There have been a number of studies showing [that] when generic drugs enter the market, that drug prices fall substantially. Money that is spent unnecessarily on expensive drugs cannot be spent in other areas of healthcare delivery.
CD: Catherine Dolf, The JAMA Report.

  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    adequate 【形容词】1. 足够的,充分的; 能满足需要(量)的 2.恰当的,适合的
  • American Medical Association 美国医学协会◆【略】AMA
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    availability 【形容词】可获得的;可用的; 空闲的,有时间的
  • charge whatever the market will bear 向市场开出可承受的最高价
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    colleague 同事【名词】同事,同行
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    competition 竞争【名词】1. 竞争; 2. 比赛,竞赛; 3. 【生物学】生存竞争
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    contribute 贡献【及物动词】1. 捐赠(款项); 2. 投稿(给杂志等); 3. 贡献出; 【不及物动词】1. 出力,作出贡献; 2. 捐款,捐献; 3. 投稿
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    delivery of care 提供医疗服务
  • dosis 服药量;剂量;一次剂量
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    drug company 制药公司
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    drug cost 药品费用
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    drug price 药品价格
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    drugged 【及物动词】用药麻醉;使服药;使服毒品
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    exclusivity 排他性【名词】排外,排外主义;排他性,排他主义(尤指搞宗派,拉山头,或闭关自守)。
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    expensive drug 昂贵的药物
  • Extracting Microarray Gene Expression Patterns and Identifying co-expressed Genes 提取微阵列基因表达模式和确认共表达基因◆【略】EPIG
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    factor 因子【名词】因素,因数,要素,系数
  • frustration 挫折
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    generic 【名词】仿制药; 【形容词】1. 【生物学】属的,类的; 2. 一般的,普通的; 3. (商品)未注册的;不受商标注册保护的; 4. 【语法】全称的,总称的
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    generic drug 仿制药; 非专利药; 通用名药
  • health policy 卫生政策
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    healthcare 医疗保健;医疗卫生;健康服务
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    hospital 医院【名词】院,住院
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    implication 含义【名词】1. 牵连,牵涉,纠缠; 2. 含蓄,含意,言外之意; 3. 【数学】蕴涵,蕴含; 4. 本质,实质; 5. 推断,结论
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    limitation 限制【名词】1. 限制; 2. 界限;极限;限度;局限性;限制因素; 3.【法律】(诉讼)时效,有效期限
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    literature 文学【名词】文献,文学作品,文学史,文献资料,文学奖,文艺
  • market exclusivity 独家营销权
  • market exclusivity period [药物]市场独占期
  • medical association 医学协会
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    medical journal 医学期刊
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    negotiate 谈判【及物动词】1. 议定,商定,通过谈判使…; 2. 卖[让]与;使(证券、票据等)流通,转让,兑现; 3. 处置;处理;克服(困难等);通过,跳通(障碍); 【不及物动词】协议,谈判,交涉
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    patient care 患者护理
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    period 1. 周期,期间 2. 月经期 3. 句号; 结束
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    pharmacy 药房 【名词】1. 配药学,药学; 2. 制药业; 3. 药房; 4. (一批)备用药品
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    physician 1. 医师,内科医生; 2. (比喻) (精神创伤的) 医治者,抚慰者
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    pill 丸【1名词】1. 丸,药丸; (the birth control pill/the pill) (女用口服)避孕丸; 2. 讨厌的东西[人];苦事; 3. (俚语)炮弹,子弹;球;(pl.)(英俚)撞球战,弹子战; 4. (美俚)香烟;切去两端的雪茄烟;(鸦片)烟泡; 5. 投票用小球; 6. 【农业】粒肥;【及物动词】1. 把…作成丸药;给…吃丸药; 2. (俚语)投票反对;排斥;不录取;开除;【及物动词】(古语)抢劫,掠夺
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    policy 政策【1名词】1. 政策; 方针 2. 策略;策略性【2名词】1. 保险单; 抽彩 2. 抽彩
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    prescribe 【及物动词】1. 处方;嘱咐(疗法) 2. 命令;指示;规定;限制 3. 【法律】使(过限期而)失效 【不及物动词】1. 开药方,给医嘱 2. 命令;指示;规定 3.【法律】(长期占有)要求权利;(因过期限而)失效
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    prescribed drug 处方药
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    prescription 【名词】1. 处方;处方的药;解救方法 2. 命令;规定;法规 3.【法律】(由于长期使用等而)获得权利 【形容词】按处方配制的◆【対】over-the-counter (OTC)
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    prescription drug 处方药
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    prescription drug prices 处方药价格
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    provision 【名词】1. 规定;条款 2.预备; 准备; 供应物 【及物动词】供应补给品
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    reasonable period 合理期限
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    resource 资源; 财力
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    shock 【名词】颤抖,战栗; 【及物动词】颤抖,打碎; 【不及物动词】 颤抖,哆嗦,打碎
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    splitting 【形容词】1. 爆裂的; 分裂; 剧痛的 2.极快的; 【名词】【数学】因式分解
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    stem 【名词】1. (草木的)茎,干; 2. 柄,把,杆; 【1及物动词】1. 除掉梗茎,2. 装上柄,杆; 【不及物动词】起源于,起因于,来自; 【2及物动词】1. 阻止,遏止,挡住; 2. (船)逆(风)开行【不及物动词】1. 堵住,止住; 2. 逆行
  • stem from 干【1及物动词】1. 除掉…的梗茎; 2. 给…装上柄、杆;给(假花等)装上梗柄;【不及物动词】起源于,起因于,(由…)发生,来自;【2及物动词】1. (船)逆(风)开行; 2. 顶着水面上;【不及物动词】1. 堵住,止住; 2. 逆行; 3. 转动滑雪屐停止滑行
  • sticker shock 标价令人瞠目结舌
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    The Journal of the American Medical Association 《美国医学协会杂志》◆【略】JAMA
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    wasting 浪费【名词】浪费;糟蹋;消耗,【医学】虚痨。wasting disease 消耗性疾病(如结核病);痨病;【形容词】消耗性的,渐减的;使荒废的;破坏性的
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