Wechat logo 50 41 d4bae92fc2b9067675bfee08d2b00834882415940f50456376420c2e77a679ac
返回

Cerebral Protection Device Effects After TAVI


Journal of the American Medical Association - July 9, 2016 新临床实验研究防栓塞装置对严重主动脉瓣狭窄患者在TAVI术期间的脑损伤防护作用。 New trial studies the cerebral embolic protection devices used during TAVI on MRI-detected brain lesions in patients with severe aortic stenosis.

点击高亮查看翻译

Catherine Dolf, Reporter, JAMA Report: A procedure is underway to replace this patient's diseased heart valve. It's called "transcatheter aortic valve implantation", or TAVI. Instead of open-heart surgery, doctors use a catheter to implant a new valve inside the old one. During this process, tissue and plaque in the blood vessels can become loose, traveling through the bloodstream to the brain.
Dr. Axel Linke, Cardiologist, University of Leipzig Heart Center: Because of the material, you have neurologic injuries and like little strokes or little cerebral infarcts.
CD: A cerebral protection device is a type of filter that is placed by catheter directly into the vessels that supply the brain.
AL: By using the filter, we are trying to capture this material and protect the brain. The device is designed to save brain tissue that would otherwise be killed by particles that occlude little vessels that supply the brain with blood and oxygen.
CD: Dr. Axel Linke of the University of Leipzig Heart Center in Germany, and co-authors, studied 100 patients with an average age of 80, who underwent the TAVI procedure. Half the patients received the filter device [and] the other half did not. They also underwent an MRI of the brain before, and again at two and seven days after the procedure.
AL: By using the filter device, the number of lesions in the brain was reduced by 50% and the volume was reduced by 50% as well.
CD: The study appears in JAMA - Journal of the American Medical Association.

AL: You're reducing the number of lesions, which means the number of holes in the brain, and you're reducing the amount of dead tissue in the brain. You have more functional neurons and more live brain tissue present, as compared to somebody without embolic protection.
CD: Catherine Dolf, the JAMA Report.

  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    after the procedure 手术治疗后;检查后
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    aging 老化【及物动词】衰老,老龄化,时效,老龄,增龄,陈酿,老年
  • American Medical Association 美国医学协会◆【略】AMA
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    aortic 【形容词】主动脉的
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    aortic valve 主动脉瓣
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    author 作者【名词】1. 著者,作家; 2. 著作物,作品; 3. 创造者;发起人; 【及物动词】1. 写,写作; 2. 创造,创始; 3. 【自动化】(在计算机上)制作(网页)
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    blood 血液【名词】1. 血,血液;生命液; 2. 血族,血统;种族;家族(关系);家世;门第;名门,门阀;贵族血统; 3. 生命,活力;元气; 4. 流血,杀戮,杀人(罪),牺牲; 5. 血气;气质,气性,脾气;热情;激怒;肉欲;兽欲; 6. (主英)血气方刚的人;花花公子,纨袴子; 7. (集合词)人员; 8. (树木、果子等的)赤色汁液;(美俚)蕃茄酱; 9. (马的)纯种
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    blood vessel 血管
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    bloodstream 【生理学】血流,(体内循环的)血液
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    brain 大脑【名词】1. 脑,(pl.)脑髓;(俚语)计算机;(导弹的)制导系统; 2. (常 pl.)智力,智能,智慧,脑力;头脑; 3. (口语)聪明人;(口语)(pl.)智囊,出谋划策者
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    brain tissue 脑组织
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    cardiologist 心脏病学家;心血管病医师
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    catheter 导管【名词】导(液)管
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    cerebral 【形容词】1. 大脑的;脑的 2. 理智方面的;非感情方面的
  • cerebral protection 脑保护
  • cerebral protection device 脑保护装置
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    co-author 合著者;合著
  • dead tissue 死亡组织
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    designing 设计【形容词】1. 狡猾的,有野心[阴谋]的; 2. 计划性的,有远见的; 【名词】设计(工作)
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    device 设备【名词】1. 设计,计划;方法,手段; 2. 意志,欲望; 3. 谋略,策略,诡计; 4. 器具,器械,设备,装置; 5. 图案,图样;花样;纹章;标记,商标;(纹章上的)题铭
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    disease 【名词】1. 病,疾病;【植物】病害 2. (精神等的)病态,弊病 3. (酒等的)变质;(食物等的)腐败
  • diseased heart 患病心脏
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    diseased heart valve 病损的心脏瓣膜
  • embolic 栓塞
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    filter 筛选器【名词】1. 滤器,滤纸,过滤用料[砂、炭等]; 2. 【无线电】滤波器;【物理学】滤光镜,滤色器;【及物动词】过滤,用过滤法除去;【不及物动词】1. 过滤; 2. 渗入,(消息)走漏; 3. (英国)(车辆在十字路口)开入另一车道
  • filter device 过滤装置
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    functional 功能【形容词】1. 官能的,机能的; 2. 在起作用的;职务上的; 3. 【数学】函数的; 4. 【建筑】从使用的观点设计[构成]的; 5. 有多种用途的;可改变用途的; 6. 可使用的,可操作的
  • functional neuron 功能性神经元
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    heart 心 【名词】1. 心脏,心; 2. 胸,胸部;心胸,心地,心肠,胸怀; 3. 感情,热情,爱情;灵魂;良心; 4. 勇气,胆力;勇士; 5. 精神,气质;心境,心情; 6. 中心,核心;精华,要点,本质; 7. 意中人,情人;心爱的人,宝贝儿; 8. (主英)(土地的)肥沃程度; 9. 心脏形的东西
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    heart surgery 心脏手术
  • heart valve 心脏瓣膜
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    implant 【名词】1. 移植物; (插入体内)植入管 【及物动词】1. 植入,移植 2. 嵌入,插入,埋置 3. 注入,灌输; 使(思想等)生根
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    implantation 【名词】1. 【医学】植入,移植;皮下注射 2. 插入; 灌输 3.【胚胎学】种植
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    infarct 梗死;梗塞
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    injury 损伤【名词】1. 损害,毁坏,伤害; 2. 伤害的行为; 3. 受伤处
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    lesion 【名词】1. 病变;损害,损伤 2. (机体、器官受损而引起的)器官损害,功能减弱;机能障碍 【及物动词】使受损伤,损害
  • living brain 活体脑
  • medical association 医学协会
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    medical journal 医学期刊
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    neurologic 神经【形容词】神经病学的
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    neuron 神经元【名词】【解剖学】神经原,神经细胞
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    occlude 咬合【及物动词】使闭塞;使堵塞;封锁;遮蔽;使不发生作用;【化学】吸藏,吸留;【气象学】使(气旋等)锢囚; 【不及物动词】(上齿与下齿)咬合;【气象学】(气旋)锢囚
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    open-heart surgery 心脏直视手术;开心手术;体外循环心脏手术
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    oxygen 氧气【名词】【化学】氧,氧气
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    particle 【名词】1. 颗粒;微粒 2. 微量,极少量 3. 【物、数】粒子;质子
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    plaque 【名词】1. 匾,饰板 2. 胸章;徽章; 3. 斑; 斑块; 粥样斑块; (噬菌体)溶菌斑; 牙菌斑
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    procedure 【名词】1. 步骤;方法;算法 2. 程序 ;常规;诉讼程序 3. 行为;做法 ;礼仪
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    processed tissue 处理组织
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    protection 保护【名词】防护,保障
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    stroke 【名词】1. 脑卒中;中风;(疾病的)发作 2. (心脏的)跳动;脉搏 3. 一击,一敲 4. 【机械】冲程,行程【1及物动词】1. (用笔)画;勾消 2. (划船比赛中) 划【2及物动词】轻抚
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    surgery 【名词】1. 外科(学);外科手术; 2. 外科手术[实验]室;(英国)医院;诊所
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    The Journal of the American Medical Association 《美国医学协会杂志》◆【略】JAMA
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    tissue 组织【名词】1. 薄绢,薄纱罗(等织物); 2. 薄纸,棉纸; 3. (编造的谎话等的)一套,一连串; 4.【摄影】碳素印像纸; 5.【生物学】组织
  • tissue in the brain 组织在大脑
  • transcatheter 经导管
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    undergo 【及物动词】1. 经受,经历,接受;2. 遭受,忍受
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    underway 正在进行【形容词】1. 【航海】在航行中的; 2. 在旅途[行进]中(发生、进行、使用)的;正在进行[工作]中的; 【副词】进行中
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    valve 阀【名词】1.【机械工程】阀,活门,舌门;汽门; 2.【解剖学;动物学】瓣,瓣膜;(贝)壳瓣;【植物;植物学】荚片;(藻的)瓣;(果实的)裂片; 3.【建筑】门的一扇; 4.【无线电】电子管,真空管
  • Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615
    vessel 船只【名词】1. 容器,器皿(桶、钵、碗等); 2. 船,舰;飞船; 3. (喻、谑)人; 4.【解剖学;动物学】管,脉管,血管;【植物;植物学】导管
Sound e31a43d441998f862b764d17930467a5a23de45c433219259bed5eb42e3a7615