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MRI Impact on Offspring in Pregnancy

Journal of the American Medical Association - September 8, 2016 MRI造影剂钆(Gd)在妊娠早期对胎儿的可能影响。 Possible effect of MRI gadolinium contrast on fetus in the first trimester of pregnancy.

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Dr. Joel Ray, St. Michael's Hospital: Hi, Lauren. Joel Ray. Nice to see you.
Laura Kelly, Reporter, The JAMA Report: Should women take a pregnancy test before having an MRI? A new study published in The Journal of the American Medical Association looked at the safety of magnetic resonance imaging during pregnancy, especially during the first trimester.
WOMAN: Are there any risks to the baby?
JR: We already have a fair amount of data on CAT scan safety in pregnancy, but MRI was lacking.
LK: Dr. Joel Ray and his colleagues at St. Michael's Hospital in Toronto analyzed data collected over 12 years and concluded that MRI in the first trimester was not harmful to the developing fetus.
JR: A first trimester MRI is unlikely to be harmful, so special pregnancy testing or measures are unlikely to be required.
LK: Women undergoing an MRI with the contrast agent gadolinium at any point during pregnancy were also included in the study. These MRIs with contrast were associated with a higher risk of fetal death and a variety of inflammatory and skin conditions in the newborn.
JR: For gadolinium, it reinforces what's, to date, an evidence-free notion that gadolinium might harm the fetus, and in this case, gadolinium contrast would be best avoided in pregnancy.
LK: This is Laura Kelly for The JAMA Report.

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